Contribution of σ70 and σN Factors to Expression of Class
Neisseria meningitidis expresses multicomponent organelles called type four pili Tfp which are key virulence factors required for attachment to human cells during carriage and disease Pilin PilE is the main component of Tfp and N meningitidis isolates either have a class I pilE locus and express pilins that undergo antigenic variation or have a class II pilE locus and express invariant